Items for "fusion protein"

Amplified anticoagulant activity of tissue factor-targeted thrombomodulin. In-vivo validation of a tissue factor-neutralizing antibody fused to soluble thrombomodulin

Tissue factor (TF) exposure is a potent pro-thrombotic trigger that initiates activation of the coagulation cascade, while thrombomodulin (TM) is a potent anticoagulant protein that limits the extent of activation...

Keywords: Tissue factor, thrombomodulin, fusion protein, Anticoagulant, rat thromboembolism