An algorithm was developed to evaluate equilibrium constants for testosterone (Te) and sex hormone-binding globulin (SHBG) or albumin from serum free testosterone (FTe) measurements performed in a panel of 30 healthy elderly men by means of a near-reference method, i.e., symmetric dialysis (affinity constants: SHBG-Te, 1.13×10 9 L/mol; albumin-Te, 4.4×10 4 L/mol)...
Keywords: dialysis, Equilibrium constant, free testosterone, sex hormone-binding globulin
06/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterKeywords: androgen excess, diagnostic value, free androgen index, free testosterone, polycystic ovary syndrome, receiver operating characteristic
02/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterBackground: The mass action law-based calculation methods for free testosterone (FT) and “bioavailable” testosterone (BAT) – routinely used for assessing androgen disorders – rely on the supposition that the sex hormone binding globulin (SHBG) molecule contains one steroid binding domain (SBD)...
Keywords: Androgenstörungen, ?bioverfügbares? Testosteron, freies Testosteron, Nomogramm, sexhormonbindendes Globulin, Testosteron
12/2006 | LaboratoriumsMedizin, Walter de Gruyter