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Items for "free testosterone"

A simple method for estimating equilibrium constants for serum testosterone binding resulting in an optimal free testosterone index for use in elderly men

An algorithm was developed to evaluate equilibrium constants for testosterone (Te) and sex hormone-binding globulin (SHBG) or albumin from serum free testosterone (FTe) measurements performed in a panel of 30 healthy elderly men by means of a near-reference method, i.e., symmetric dialysis (affinity constants: SHBG-Te, 1.13×10 9 L/mol; albumin-Te, 4.4×10 4 L/mol)...

Keywords: dialysis, Equilibrium constant, free testosterone, sex hormone-binding globulin

06/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Diagnostic value of calculated testosterone indices in the assessment of polycystic ovary syndrome

Background: One of the main criteria to establish a diagnosis of polycystic ovary syndrome (PCOS) is hyperandrogenemia...

Keywords: androgen excess, diagnostic value, free androgen index, free testosterone, polycystic ovary syndrome, receiver operating characteristic

02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Impact of recent biochemical findings on the determination of free and bioavailable testosterone: evaluation and proposal for clinical use

Background: The mass action law-based calculation methods for free testosterone (FT) and “bioavailable” testosterone (BAT) – routinely used for assessing androgen disorders – rely on the supposition that the sex hormone binding globulin (SHBG) molecule contains one steroid binding domain (SBD)...

Keywords: Androgenstörungen, ?bioverfügbares? Testosteron, freies Testosteron, Nomogramm, sexhormonbindendes Globulin, Testosteron

12/2006 | LaboratoriumsMedizin, Walter de Gruyter