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Items for "FOXM1c"

Transcription factor FOXM1c is repressed by RB and activated by cyclin D1/Cdk4

The proliferation-stimulating transactivator FOXM1c (MPP2) is repressed by RB and activated by cyclin D1/Cdk4 and therefore behaves like E2F...

Keywords: cyclin D1/Cdk4, cyclin E/Cdk2, FOXM1c, RB

07/2006 | Biological Chemistry, Walter de Gruyter
Despite its strong transactivation domain, transcription factor FOXM1c is kept almost inactive by two different inhibitory domains

FOXM1c (MPP2) is an activating transcription factor with several nuclear localization signals, a forkhead domain for DNA binding, and a very strong acidic transactivation domain...

Keywords: forkhead box, FOXM1c, transactivation domain, transcription factor, transrepression domain, winged helix

07/2006 | Biological Chemistry, Walter de Gruyter