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Items for "fibrinogen"

Perioperative management of coagulation

Guidelines of official societies for diagnosis and therapy of intraoperatively occurring hypocoagulability rely mainly on data of patients receiving whole blood transfusions...

Keywords: Hämostase, Labormethoden, PT, aPTT, Fibrinogen, Blutverlust, Volumentherapie, Thrombelastographie/Thrombelastometrie, TEG, ROTEM

01/2006 | Hämostaseologie, Schattauer

Gender differences in the expression of erythrocyte aggregation in relation to B-fibrinogen gene polymorphisms in apparently healthy individuals

An increased erythrocyte aggregation (EA) is associated with capillary slow flow, tissue hypoxemia and endothelial dysfunction...

Keywords: Erythrocyte aggregation, fibrinogen, gene polymorphism

03/2006 | Thrombosis and Haemostasis, Schattauer

Identification of a new truncated form and deamidation products of fibrinopeptide B released by thrombin from human fibrinogen

Quantification of fibrinopeptides release is widely used to investigate fibrinogen activation, and standard chromatographic or capillary electrophoretic procedures are readily available...

Keywords: blood coagulation, human, fibrinogen, fibrinopeptides, chromatography, Mass spectrometry

09/2006 | Thrombosis and Haemostasis, Schattauer

The effect of glycaemic control on fibrin network structure of type 2 diabetic subjects

Diabetic subjects have been shown to have altered fibrin network structures. One possible cause may be fibrinogen glycation resulting in altered structure/function properties...

Keywords: diabetes, glycation, fibrinogen, fibrin network structure, glucose control

11/2006 | Thrombosis and Haemostasis, Schattauer

Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: The Rotterdam Study

Fibrin network structure has been correlated with coronary disease. Fibrinogen and (FGG and FGA) gene haplotypes (chromosome 4q28) may be associated with fibrin network structure, and thereby with rigidity of the fibrin clot and sensitivity of the fibrin clot to the fibrinolytic system...

Keywords: Coronary disease, atherosclerosis, epidemiology, genetics, fibrinogen

00/0000 | Thrombosis and Haemostasis, Schattauer

Mutational screening of six afibrinogenemic patients: Identification and characterization of four novel molecular defects

Congenital afibrinogenemia (CAF) is a rare coagulation disorder characterized by very low or unmeasurable levels of functional and immunoreactive fibrinogen in plasma, associated with a hemorrhagic phenotype of variable severity...

Keywords: fibrinogen, congenital afibrinogenemia, mutational screening, large deletion, point mutations

04/2007 | Thrombosis and Haemostasis, Schattauer

Comparison of TEST 1 with SRS 100 and ICSH reference method for the measurement of the length of sedimentation reaction in blood

Background: We evaluated the measurement of length of sedimentation reaction in blood (LSRB) by TEST 1 and compared the results with those for the Westergren and Sed Rate Screener 100 (SRS 100) methods.

Methods: LSRB was measured in 113 paired blood samples.

Results: TEST 1 correlated significantly with the Westergren (r=0.94) and SRS 100 (r=0.90) methods with low bias (?0.29 and ?1.92 mm/h, respectively) and limits of agreement (?14.5 to 13.9, and ?23.4 to 19.6 mm/h, respectively)...

Keywords: fibrinogen, hematocrit, length of sedimentation reaction, TEST 1, Westergren method

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Polymorphisms associated with apolipoprotein B levels in Greek patients with familial hypercholesterolemia

Background: Familial hypercholesterolemia (FH) is a genetic disorder characterized by high low-density lipoprotein-cholesterol (LDL-C) concentrations, which frequently gives rise to premature coronary artery disease...

Keywords: apolipoprotein B, familial hypercholesterolemia, fibrinogen, lipoprotein lipase, paroxonase, polymorphisms

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Determination of the length of sedimentation reaction in blood using the TEST 1 system: comparison with the Sedimatic 100 method, turbidimetric fibrinogen levels, and the influence of M-proteins

Background: Determination of the length of sedimentation reaction in blood (LSRB) is frequently used in daily practice to assess disease intensity...

Keywords: fibrinogen, length of sedimentation reaction in blood, M-proteins, rheumatological diseases, TEST 1, Westergren method

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Aggregation of lipoprotein and inflammatory parameters in families with a history of premature myocardial infarction: the Tallinn Myocardial Infarction Study

Background: The offspring of individuals with a history of premature myocardial infarction are at increased risk of premature coronary attacks...

Keywords: apolipoprotein E polymorphism, C-reactive protein, fibrinogen, lipoprotein(a), offspring of survivors of myocardial infarction

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Can both EDTA and citrate plasma samples be used in measurements of fibrinogen and C-reactive protein concentrations?

Background: Fibrinogen and C-reactive protein (CRP) concentrations are predictors of outcome in the atherosclerotic patient...

Keywords: Citrate, C-reactive protein, EDTA, fibrinogen

08/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

The molecular basis of homocysteine thiolactone-mediated vascular disease

Accumulating evidence suggests that a metabolite of homocysteine (Hcy), the thioester Hcy-thiolactone, plays an important role in atherogenesis and thrombosis...

Keywords: atherosclerosis, autoantibodies, cystathionine ?-synthase (CBS), dietary hyperhomocysteinemia, fibrinogen, genetic hyperhomocysteinemia, homocysteine thiolactone hypothesis, immune activation, methylenetetrahydrofolate reductase (MTHFR), protein N-homocysteinylation, thrombosis

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Diagnostische Möglichkeiten und Grenzen der Thrombelastographie/-metrie / Diagnostic potential and limitations of thrombelastography/-metry

Zusammenfassung Im Gegensatz zu den klassischen Gerinnungsparametern ermöglicht die Thrombelastographie/-metrie auch eine Beurteilung der Gerinnselfestigkeit und -stabilität...

Keywords: Clotfestigkeit, fibrinogen, Hyperfibrinolyse, Rotationsthrombelastometrie, Thrombozyten, clot strength, hyperfibrinolysis, thrombelastography/-metry, thrombocytes

12/2007 | LaboratoriumsMedizin, Walter de Gruyter

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Items for "fibrinogen"