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Items for "factor XIII"

Evaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice

Thrombin-activated Factor XIII (FXIIIa), a plasma transglutaminase, stabilizes fibrin clots by crosslinking fibrin chains...

Keywords: Angiogenesis, factor XIII, thrombospondin-1

03/2006 | Thrombosis and Haemostasis, Schattauer

Mutations in coagulation factor XIII A gene in eight unrelated Indians. Five novel mutations identified by a novel PCR-CSGE approach

Factor XIII deficiency is a rare autosomal (1:2,000,000) recessive disorder of blood coagulation usually attributed to mutations in the coagulation factor XIII (FXIII) A gene...

Keywords: factor XIII, mutation, CSGE

03/2006 | Thrombosis and Haemostasis, Schattauer

Factor XIII Val34Leu variant protects against coronary artery disease. A meta-analysis

Several studies suggested that Val34Leu variant of factor XIII (FXIII) might have a protective effect against coronary artery disease (CAD), but studies not supporting these findings have also been published...

Keywords: Coronary disease, factor XIII, Polymorphism, meta-analysis

03/2007 | Thrombosis and Haemostasis, Schattauer

Factor XIII Val34Leu variant and the risk of myocardial infarction. A meta-analysis

Genetic factors are thought to contribute to the pathogenesis of acute myocardial infarction (AMI). A common variant of factor XIII (FXIII), FXIII Val34Leu, may be protective against developing an AMI, but various studies show conflicting results...

Keywords: factor XIII, genetic, meta-analysis, myocardial infarction, risk factor

04/2007 | Thrombosis and Haemostasis, Schattauer

Rapid detection of the factor XIII Val34Leu (163 G?T) polymorphism by real-time PCR using fluorescence resonance energy transfer detection and melting curve analysis

The Val34Leu polymorphism in the A subunit of blood coagulation factor XIII (FXIII-A) is located in the activation peptide, just three amino acids upstream of the thrombin cleavage site...

Keywords: factor XIII, fluorescence resonance energy transfer, gene polymorphism, real-time PCR

08/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter