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Items for "factor X"

The influence of sodium ion binding on factor IXa activity

Sodium plays an important role in modulating both the amidolytic and proteolytic activities of thrombin...

Keywords: Factor IXa, factor X, intrinsic Xase, sodium, calcium

06/2006 | Thrombosis and Haemostasis, Schattauer
Platelet microparticle membranes have 50- to 100-fold higher specific procoagulant activity than activated platelets

Platelet microparticles (PMPs) are small vesicles released from blood platelets upon activation. The procoagulant activity of PMPs has been previously mainly characterized by their ability to bind coagulation factors VIII and Va in reconstructed systems...

Keywords: Platelet, PMPs, procoagulant activity, spatial dynamics of coagulation, thrombin generation, factor X, phosphatidylserine, CD-61, CD-62P

03/2007 | Thrombosis and Haemostasis, Schattauer