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Keywords: extracellular signal-regulated kinase (ERK), Migration, phosphatidylinositol 3-kinase (PI3-K), Rho GTPases, signal transduction, transformation
03/2005 | Biological Chemistry, Walter de GruyterExposure of rat liver epithelial cells to doxorubicin, an anthraquinone derivative widely employed in cancer chemotherapy, led to a dose-dependent decrease in gap junctional intercellular communication (GJC)...
Keywords: connexin-43, extracellular signal-regulated kinase (ERK), gap junction, mitogen-activated protein (MAP) kinase, oxidative stress, signal transduction, stress signaling
03/2005 | Biological Chemistry, Walter de GruyterAdvanced malignancies often exhibit increased concentrations of transforming growth factor-? (TGF?), which has been suggested to promote invasion and metastasis...
Keywords: epithelial dedifferentiation, extracellular signal-regulated kinase (ERK), focal complex formation, Rho-GTPases, signal transduction, transforming growth factor-? (TGF?)
03/2005 | Biological Chemistry, Walter de Gruyter