Items for "exclusion"

Paternal exclusion: allele sharing in microsatellite testing

Background: A paternity disagreement analyzed with 15 autosomal microsatellite markers indicated allele sharing between the mother, questioned child and the alleged father generating an inconclusive paternity result.

Design and methods: In total, 15 autosomal and 17 Y tandem repeat loci were analyzed using AmpFlSTR Identifiler, AmpFlSTR^®Y-filer? kits followed by six microsatellite markers on X chromosome in DNA extracted from peripheral blood samples of the mother, questioned child and alleged father.

Results: Microsatellite analysis examined with 15 autosomal short tandem repeats (STRs) indicated at least one allele sharing at 14 loci between the mother, questioned child and alleged father except for the TPOX locus where a paternal-child allele mismatch was observed...

Keywords: allele sharing, exclusion, mismatch, paternity testing, short tandem repeats (STRs), X-STR, Y-STR