Items for "excitotoxicity"

The molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function

Selenoproteins have been recognized as modulators of brain function and signaling. Phospholipid hydroperoxide glutathione peroxidase (GPx4/PHGPx) is a unique member of selenium-dependent glutathione peroxidases in mammals with a pivotal role for brain development and function...

Keywords: Apoptosis, embryogenesis, excitotoxicity, glial cells, oxidative stress, phosphoinositides, selenium