Females live longer than males. We have shown that the higher levels of estrogens in females protect them against aging, by up-regulating the expression of antioxidant, longevity-related genes, such as that of selenium-dependent glutathione peroxidase (GPx) and Mn-superoxide dismutase (Mn-SOD)...
Keywords: aging, antioxidant enzymes, estrogenic compounds, free radicals, gender, oxidative stress
03/2008 | Biological Chemistry, Walter de Gruyter