An intricate interplay between the genes encoding fibrinogen gamma (FGG), alpha (FGA) and beta (FGB), coagulation factor XIII (F13A1) and interleukin 6 (IL6) and environmental factors is likely to influence plasma fibrinogen concentration, fibrin clot structure and risk of myocardial infarction (MI)...
Keywords: Epistasis, fibrinogen clot structure, myocardial infarction, plasma fibrinogen concentration, pleiotropy
03/2006 | Thrombosis and Haemostasis, SchattauerThe Human Genome and HapMap projects have provided the tools and information that will aid in understanding how nutrients alter the expression of an individual's genetic information and why individuals differ in metabolism of foods at the molecular level...
Keywords: Epistasis, gene-nutrient interactions, genetics, nutrigenomics, nutrition
03/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter