Items for "epidermal lipid barrier breakdown"

Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1^-/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation

Targeted deletion of the stearoyl-CoA desaturase 1 gene (scd1) in mouse causes obesity resistance and a severe skin phenotype...

Keywords: dysregulation of thermogenesis, epidermal lipid barrier breakdown, hypermetabolism, obesity resistance, SCD1 deficiency, VLCFA synthesis