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Items for "epidemiology"

Stroke: epidemiology, risk factors, and genetics

Stroke constitutes a major global challenge for health policy and healthcare economics. Reducing stroke burden requires extensive knowledge of risk factors and, if applicable, preventive control...

Keywords: Schlaganfall, Epidemiologie, Risikofaktoren, Genetik

01/2006 | Hämostaseologie, Schattauer
Bioinformatics: Towards New Directions for Public Health

OBJECTIVES: Epidemiologists are reformulating their classical approaches to diseases by considering various issues associated to omics areas and technologies...

Keywords: Public Health, bioinformatics, epidemiology, Genomics, Medical Informatics

01/2004 | Methods of Information in Medicine, Schattauer
The SARS Epidemic in Hong Kong A Human Calamity in the 21st Century

PURPOSE: This paper reviews the epidemiology and control measures of the SARS epidemic in Hong Kong. It sets out proposals for better preparedness to tackle the disease in future...

Keywords: SARS, epidemiology, etology, informatics, control, surveillance

01/2005 | Methods of Information in Medicine, Schattauer
Genetic Epidemiology in Germany From Biobanking to Genetic Statistics

Objectives: Genetic epidemiology investigates the role of genetic factors and their interaction with environmental factors (in a broad meaning) for the occurrence of diseases in human populations...

Keywords: Biobanking, genetics, epidemiology, bioethics

01/2005 | Methods of Information in Medicine, Schattauer
A Scoring System for Ascertainment of Incident Stroke; the Risk Index Score (RISc)

Objectives: The main objective of this study was to develop and validate a computer-based statistical algorithm that could be translated into a simple scoring system in order to ascertain incident stroke cases using hospital admission medical records data. Methods: The Risk Index Score (RISc) algorithm was developed using data collected prospectively by the Brain Attack Surveillance in Corpus Christi (BASIC) project, 2000...

Keywords: Stroke, epidemiology, screening, surveillance, informatics

01/2006 | Methods of Information in Medicine, Schattauer
Racial and gender differences in the incidence of recurrent venous thromboembolism

Men have been reported to have a higher incidence of recurrent venous thromboembolism than women. However, it is not known if this gender effect holds among different racial/ethnic groups and for both venous thrombosis and pulmonary embolism...

Keywords: Race, ethnicity, gender, recurrent thromboembolism, epidemiology

09/2006 | Thrombosis and Haemostasis, Schattauer
Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: The Rotterdam Study

Fibrin network structure has been correlated with coronary disease. Fibrinogen and (FGG and FGA) gene haplotypes (chromosome 4q28) may be associated with fibrin network structure, and thereby with rigidity of the fibrin clot and sensitivity of the fibrin clot to the fibrinolytic system...

Keywords: Coronary disease, atherosclerosis, epidemiology, genetics, fibrinogen

00/0000 | Thrombosis and Haemostasis, Schattauer
The 11377 C > G promoter variant of the adiponectin gene, prevalence of coronary atherosclerosis, and incidence of vascular events in men

No prospective data demonstrating an association between the 11377 C > G adiponectin gene promoter variant and cardiovascular risk are available...

Keywords: coronary artery disease, angiography, risk factors, cytokines, epidemiology

03/2007 | Thrombosis and Haemostasis, Schattauer
Peripheral blood mononuclear cells (PBMCs): a possible model for studying cardiovascular biology systems

Background: The inflammation system, alone or in relation to or interaction with other cardiovascular pathways, is suggested to be the central pathway in the development and progression of cardiovascular diseases...

Keywords: cardiovascular metabolic pathways, epidemiology, gene expression inflammation, peripheral blood mononuclear cells (PBMCs)

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio

Cytochrome P450 (CYP) is a multigene family of enzymes involved in important life functions; some of these genes are inducible and are implicated in the oxidative metabolic activation and detoxification of many endogenous and exogenous compounds. CYP1B1 codes for an enzyme that catalyses the production of a 2- and 4-hydroxyl group in estrone and estradiol, while CYP1A1 catalyzes the 2-hydroxylation of estradiol in endometrium...

Keywords: chemoprevention, epidemiology, estrogen metabolism, transitional study

07/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Homocysteine and heart failure: a review of investigations from the Framingham Heart Study

High plasma homocysteine levels are associated with a moderately increased risk of cardiovascular disease, particularly of atherosclerotic events...

Keywords: epidemiology, Heart failure, homocysteine, left ventricular hypertrophy

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Die Diagnostik der Toxocara-Infestationen und der Toxokarose des Menschen The diagnosis of Toxocara infestations and of human toxocarosis

Zusammenfassung

Die beiden Askariden-Spezies Toxocara canis (Hundespulwurm) und T...

Keywords: Diagnostik, Epidemiologie, gemeine Toxokarose, inapparente Toxokarose, Klinik, Larva migrans visceralis-Syndrom, okuläres Larva migrans-Syndrom, Pathogenese, T. cati, Therapie, Toxocara canis, Toxokarose, zerebrale Toxokarose, cerebral toxocarosis, clinical aspects, common toxocarosis, covert toxocarosis, diagnosis, epidemiology, Larva migrans visceralis syndrome, ocular Larva migrans syndrome, pathogenesis, therapy, toxocarosis

03/2006 | LaboratoriumsMedizin, Walter de Gruyter
Schilddrüsenfunktion und -dysfunktion im Alter / Thyroid function and dysfunction in the elderly

Zusammenfassung

Die vorliegende Übersichtsarbeit gibt den momentanen Stand des Wissens über die Funktion und Dysfunktion der Schilddrüse im Alter wieder...

Keywords: Alter, Epidemiologie, Labordiagnostik, Oligosymptomatik des Alters, Schilddrüse, Schilddrüsendysfunktion, Schilddrüsentherapie, epidemiology, laboratory diagnosis, old age, oligosymptomatology, thyroid dysfunction, Thyroid function

02/2007 | LaboratoriumsMedizin, Walter de Gruyter
Freie Fettsuren als kardiovaskulrer Risikofaktor / Free fatty acids as a cardiovascular risk factor

Zusammenfassung Freie Fettsuren (FFS) sind physiologisch wichtige Energiesubstrate, deren Freisetzung durch Lipolyse im Fettgewebe an die Energiebedrfnisse des Krpers angepasst ist...

Keywords: Epidemiologie, freie Fettsuren, kardiovaskulre Erkrankungen, cardiovascular disorders, epidemiology, free fatty acids

06/2007 | LaboratoriumsMedizin, Walter de Gruyter
PopGen – Population-based Recruitment of Patients and Controls for the Analysis of Complex Genotype-phenotype Relationships

The relative risks of genetic variants associated with complex human diseases can be efficiently assessed by the complete ascertainment of cases in a confined geographical region...

Keywords: Biology and Genetics, epidemiology, biobanks, complex disease, relative risk

06/2007 | it – Information Technology (vormals it+ti), Oldenbourg Wissenschaftsverlag
Biobanks in Genetic-epidemiological Research such as KORA-gen

Biobanks are an important tool of genetic epidemiology, which investigates the role of genetic factors and their interaction with environmental factors (in a broad meaning) for the occurrence of diseases in human populations...

Keywords: biobanks, genetics, epidemiology, biostatistics, bioethics

06/2007 | it – Information Technology (vormals it+ti), Oldenbourg Wissenschaftsverlag