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Items for "enzyme activity"

Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum

We have previously presented evidence that two human kallikrein-related peptidases, KLK5 (hK5, stratum corneum tryptic enzyme, SCTE) and KLK7 (hK7, stratum corneum chymotryptic enzyme, SCCE), which are abundant in the stratum corneum, may be involved in desquamation...

Keywords: desquamation, enzyme activity, hK5/KLK5/SCTE, hK7/KLK7/SCCE, hK14/KLK14, stratum corneum

06/2006 | Biological Chemistry, Walter de Gruyter

Characterization of peptidyl-tRNA hydrolase encoded by open reading frame Rv1014c of Mycobacterium tuberculosis H37Rv

The enzyme peptidyl-tRNA hydrolase (Pth, EC 3.1.1.29) is essential for the viability of bacteria...

Keywords: complementation, enzyme activity, molecular modeling, mutagenesis, peptidyl-tRNA hydrolase, thermal unfolding

05/2007 | Biological Chemistry, Walter de Gruyter

Enzymatic properties of human kallikrein-related peptidase 12 (KLK12)

Human kallikrein-related peptidase 12 (KLK12) is a new member of the human tissue kallikrein family...

Keywords: enzyme activity, enzyme cascades, serine proteases, tissue kallikreins, trypsin-like activity, tumor markers

04/2007 | Biological Chemistry, Walter de Gruyter

External Quality Assessment in The Netherlands: time to introduce commutable survey specimens. Lessons from the Dutch “Calibration 2000” project

The performance of suitable secondary reference material for the use of trueness control of six routinely measured clinical enzymes in the Dutch External Quality Assessment (EQA) scheme is described...

Keywords: calibration, commutability, enzyme activity, External Quality Assessment, reference materials

03/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Thiopurine S-methyltransferase (TPMT) pharmacogenetics: three new mutations and haplotype analysis in the Estonian population

Background: Thiopurine methyltransferase (TPMT) is a cytoplasmic enzyme involved in the metabolism of thiopurine drugs...

Keywords: enzyme activity, haplotype analysis, pharmacogenetics, thiopurine methyltransferase (TPMT)

07/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter