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Items for "endothelin-1"

Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies

Membrane-bound peptidases play a key role in the control of growth, differentiation, and signal transduction of many cellular systems by degrading bioactive peptides...

Keywords: aminopeptidase, angiotensin II, bioactive peptide, Cancer, endothelin-1, oxytocin

08/2004 | Biological Chemistry, Walter de Gruyter

Plasma endothelin-1 and clinical manifestations of neonatal sepsis

Aim: To determine whether plasma endothelin-1 (ET-1) relates to clinical manifestations of sepsis in the newborn, especially with systemic hypotension, acidosis, severe hypoxemia (which may represent pulmonary hypertension) and oliguria.

Methods: Prospective study of 35 consecutive newborns with clinical sepsis: 22 with hemoculture-positive (HC+) sepsis and 13 hemoculture-negative (HC–)...

Keywords: endothelin-1, hypoxemia, Newborn, oliguria, pulmonary hypertension, sepsis, seizures, SNAP-II, systemic hypotension

11/2004 | Journal of Perinatal Medicine, Walter de Gruyter

Endothelin-1 concentrations in cord blood of neonates with meconium-stained amniotic fluid

Background: The effects of meconium-stained amniotic fluid (MSAF) on cord blood endothelin-1 (ET-1) concentrations have not been explored.

Objective: The aim of this study was to verify whether MSAF influences ET-1 cord blood concentrations in healthy term neonates.

Methods: Using an enzyme-linked immunosorbent assay, plasma ET-1 concentrations were determined in 30 healthy term neonates with MSAF, and in 15 healthy term neonates without MSAF...

Keywords: endothelin-1, meconium-stained amniotic fluid, neonate

05/2005 | Journal of Perinatal Medicine, Walter de Gruyter

Association of endothelin-1 gene polymorphisms with variant angina in Korean patients

Background: The incidence of variant angina in oriental patients is higher than in patients from the Western world...

Keywords: +138delA polymorphism, endothelin-1, G8002A polymorphism, Lys198Asn polymorphism, variant angina