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Endothelial cells
Items for "Endothelial cells"
Human endothelial cells synthesize protein Z, but not the protein Z dependent inhibitor
Protein Z (PZ) is a vitamin K-dependent protein isolated from human plasma, and acts as a cofactor for a serpin, called protein Z-dependent protease inhibitor (ZPI)...
Keywords: Coagulation inhibitors, Endothelial cells, cytokines
03/2006 | Thrombosis and Haemostasis, SchattauerAnti-angiogenesis mediated by angiostatin K13, K14 and K14.5. Involvement of p53, FasL, AKT and mRNA deregulation
The molecular mechanism mediated by multiple forms of angiostatin via acting on proliferating vascular endothelium remains elusive...
Keywords: Angiostatin, Endothelial cells, AKT, p53, FasL
04/2006 | Thrombosis and Haemostasis, SchattauerSuccessful silencing of plasminogen activator inhibitor-1 in human vascular endothelial cells using small interfering RNA
Clinical as well as experimental evidence suggests that vascular overexpression of plasminogen activator inhibitor (PAI)-1, the primary physiological inhibitor of both urokinase and tissuetype plasminogen activator, may be involved in the pathophysiology of atherosclerosis and cardiovascular disease...
Keywords: Cell adhesion, fibrinolysis, Endothelial cells, plasminogen activator inhibitor-1, RNA interference
05/2006 | Thrombosis and Haemostasis, SchattauerDetection and quantification of mature circulating endothelial cells using flow cytometry and immunomagnetic beads: A methodological comparison
Mature circulating endothelial cells (CECs) are novel cellular markers of endothelial damage/dysfunction...
Keywords: Circulating endothelial cells, Endothelial cells, immunomagnetic beads, flow cytometry
07/2006 | Thrombosis and Haemostasis, SchattauerTherapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): Regulation of ALK-1/endoglin pathway in endothelial cells
Recurrent epistaxis is the most frequent clinical manifestation of hereditary haemorrhagic telangiectasia (HHT)...
Keywords: Endothelial cells, HHT, endoglin, ALK-1, tranexamic acid, fibrinolysis
00/0000 | Thrombosis and Haemostasis, SchattauerInflammatory profile of oxidized phospholipids
Lipid oxidation products and in particular oxidized phospholipids (OxPL) are increasingly recognized as inducers of chronic inflammation characteristic of atherosclerosis...
Keywords: Endothelial cells, phospholipids, inflammation
03/2007 | Thrombosis and Haemostasis, SchattauerResolution of inflammation: Intracellular feedback loops in the endothelium
Timely termination of the inflammatory reaction is equally important as its elicitation, since a persistent or exaggerated response may lead to detrimental effects in the affected tissues and organs...
Keywords: Endothelial cells, signal transduction, inflammation
03/2007 | Thrombosis and Haemostasis, SchattauerUbiquitylation within signaling pathways in- and outside of inflammation
Ubiquitin is a highly conserved 76-amino-acid peptide that becomes covalently attached to lysine residues of target proteins...
Keywords: Endothelial cells, signal transduction, inflammation
03/2007 | Thrombosis and Haemostasis, SchattauerFluorescent proteins and fluorescence resonance energy transfer (FRET) as tools in signaling research
The advent of fluorescent proteins has revolutionized signaling research, shifting focus from biochemical assays to analysis of live cells, organized tissues and even entire organisms...
Keywords: Endothelial cells, signal transduction, protein trafficking
03/2007 | Thrombosis and Haemostasis, SchattauerMolecular identification and pharmacological profile of the bovine kinin B1 receptor
To support the study of kinin pharmacology in bovine models of cultured endothelial cells (ECs), the Bovine Genome Project was searched for a B1 receptor (B1R) gene ortholog (
Keywords: bovine genome, Endothelial cells, kinin B1 receptor, pharmacological antagonism
02/2006 | Biological Chemistry, Walter de Gruyter