Human A549 lung epithelial cells were challenged with 18O-labeled hydrogen peroxide ([18O]-H2O2), the total RNA and DNA extracted in parallel, and analyzed for 18O-labeled 8-oxo-7,8-dihydroguanosine ([18O]-8-oxoGuo) and 8-oxo-7,8-dihydro-2?-deoxyguanosine ([18O]-8-oxodGuo) respectively, using high-performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-MS/MS)...
Keywords: A549 cells, electrospray ionization, Mass spectrometry, oxidative stress, 8-oxodGuo, 8-oxoGuo
04/2005 | Biological Chemistry, Walter de GruyterIn the framework of nuclear waste reprocessing, separation processes of minor actinides from fission products are developed using liquid–liquid extraction...
Keywords: electrospray ionization, Mass spectrometry, Dialkylphosphoric acid, Lanthanide, Quantum chemistry
02/2008 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag