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Items for "elastase"

Activation of the kallikrein-kinin system and release of new kinins through alternative cleavage of kininogens by microbial and human cell proteinases

Kinins are released from kininogens through the activation of the Hageman factor-prekallikrein system or by tissue kallikrein...

Keywords: allergy, elastase, gingipain, infection, mite, tryptase

11/2004 | Biological Chemistry, Walter de Gruyter

Helicobacter pylori-induced downregulation of the secretory leukocyte protease inhibitor (SLPI) in gastric epithelial cell lines and its functional relevance for H. pylori-mediated diseases

The secretory leukocyte protease inhibitor (SLPI) exerts antiproteolytic activity towards serine proteases, as well as anti-microbial and anti-inflammatory effects...

Keywords: elastase, gastric cell lines, H. pylori infection, serine proteases, SLPI

07/2006 | Biological Chemistry, Walter de Gruyter

Kunitz-type Bauhinia bauhinioides inhibitors devoid of disulfide bridges: isolation of the cDNAs, heterologous expression and structural studies

Bauhinia bauhinoides cruzipain inhibitor (BbCI) and Bauhinia bauhinioides kallikrein inhibitor (BbKI) are cysteine and serine proteinase inhibitors structurally homologous to plant Kunitz-type inhibitors, but are devoid of disulfide bridges...

Keywords: cathepsins, cruzipain, elastase, gene, kallikreins, proteinase inhibitors

06/2005 | Biological Chemistry, Walter de Gruyter

Effects of elastase and cathepsin G on the levels of membrane and soluble TNF?

Neutrophil elastase (NE) and cathepsin G (CG), the proteolytic enzymes localized in azurophil granules of neutrophils (PMN), are involved in PMN responses to various stimuli...

Keywords: cathepsin G, elastase, inflammation, neutrophil, shedding, tumor necrosis factor ? (TNF?)

08/2005 | Biological Chemistry, Walter de Gruyter

Pathophysiology and diagnostic value of urinary trypsin inhibitors

Inflammation is an important indicator of tissue injury. In the acute form, there is usually accumulation of fluids and plasma components in the affected tissues...

Keywords: antiprotease, autoimmune disease, bikunin, C-reactive protein, chondroitin sulfate, elastase, infection, inflammation, inter-?-inhibitor, pro-enzyme, proteolytic enzyme, protease-activated receptor, serine protease, urinary trypsin inhibitor

01/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter