Items for "diphenhydramine"

Histamine induces the expression of uncoupling protein 2 (UCP2) and acid-binding protein (aP2) in white adipocytes

Background: The aim of the present study was to investigate whether histamine induces up-regulated expression of uncoupling protein 2 (UCP2) and fat acid-binding protein (aP2) in white adipocytes (differentiated 3T3-L1 cells).

Methods: Differentiation of 3T3-L1 preadipocytes to adipocytes was induced by the addition of 5 ?g/mL insulin, 1 ?mol/L dexamethasone, 10 mmol/L 1-isobutyl-3-methylxanthine, 1% dimethylsulfoxide, and 10% fetal bovine serum in Dulbecco's modification of Eagle's medium...

Keywords: acid-binding protein (aP2), adipocyte, differentiation, diphenhydramine, histamine, uncoupling protein 2 (UCP2)