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Items for "diabetes"

Application of a Prediction Model for Identification of Individuals at Diabetic Risk

As a follow-up to our preceding paper, we attempted to extract features of health risk progression for diabetes in Sequential Multi Layered Perceptron (SMLP) via inverse processing of the learned structure...

Keywords: Precursors, diabetes, time-varying, SMLP, screening, health risk appraisal

01/2004 | Methods of Information in Medicine, Schattauer
Abductive Network Committees for Improved Classification of Medical Data

OBJECTIVES: To introduce abductive network classifier committees as an ensemble method for improving classification accuracy in medical diagnosis...

Keywords: Abductive networks, Neural Networks, ensemble methods, network committee, committee of experts, classification accuracy, medical diagnosis, diabetes, heart disease, dermatology

01/2004 | Methods of Information in Medicine, Schattauer
Is normal gastric emptying a predictor of normal gastric function?

Aim: Impaired gastric emptying is common in many disorders. Assuming that gastric disorders primarily affect gastric peristalsis, which secondarily results in impaired emptying, the aim of our study was to evaluate whether quantitative analysis of gastric peristalsis might be a more sensitive parameter than gastric emptying to demonstrate functional gastric impairment...

Keywords: Magenentleerung, Magenperistaltik, Diabetes mellitus, progressive systemische Sklerodermie, Gastritis

01/2005 | Nuklearmedizin, Schattauer
The effect of glycaemic control on fibrin network structure of type 2 diabetic subjects

Diabetic subjects have been shown to have altered fibrin network structures. One possible cause may be fibrinogen glycation resulting in altered structure/function properties...

Keywords: diabetes, glycation, fibrinogen, fibrin network structure, glucose control

11/2006 | Thrombosis and Haemostasis, Schattauer
Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function

Kinins are potent vasoactive peptides generated in blood and tissues by the kallikrein serine proteases...

Keywords: diabetes, glucose, insulin, kinin B1 receptor, kinins, pancreas

04/2006 | Biological Chemistry, Walter de Gruyter
The efficacy of cystatin C assay in the prediction of glomerular filtration rate. Is it a more reliable marker for renal failure?

We determined the sensitivity, specificity, receiver operating characteristics and correlation between cystatin C (cysC) and two widely used markers of renal function, creatinine clearance and serum creatinine, in 244 patients (84 diabetics, 84 hypertensive and 76 healthy subjects)...

Keywords: creatinine, cystatin C, diabetes, glomerular filtration rate (GFR), hypertension

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Homocysteine and vascular disease in diabetes: a double hit?

Cardiovascular disease is a major problem in diabetes, and risk factors presumably unrelated to diabetes, such as hyperhomocysteinaemia, may be related to the development of cardiovascular complications in diabetic individuals...

Keywords: cardiovascular disease, diabetes, endothelial function, homocysteine, oxidative stress

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Simple PCR heteroduplex, SSCP mutation screening methods for the detection of novel catalase mutations in Hungarian patients with type 2 diabetes mellitus

Background: The enzyme catalase is the main regulator of hydrogen peroxide metabolism...

Keywords: catalase gene, diabetes, nucleotide sequence, oxidative stress, PCR heteroduplex, PCR-SSCP

12/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Circulating levels of nitrated apolipoprotein A-I are increased in type 2 diabetic patients

Recent work has shown that high-density lipoprotein (HDL) isolated from human atherosclerotic lesions and the blood of patients with established coronary artery disease contains elevated levels of 3-nitrotyrosine and 3-chlorotyrosine...

Keywords: diabetes, high-density lipoprotein (HDL), macroangiopathy, myeloperoxidase, nitrosative stress, peroxynitrite

06/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Nitration of human plasminogen by RAW 264.7 macrophages reduces streptokinase-induced plasmin activity

Despite many years of study, clinical trials of new drugs to prevent thrombosis have often been disappointing...

Keywords: atherosclerosis, diabetes, fibrinolysis, nitrosative stress, peroxynitrite, phagocytes

02/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Oxidative stress evaluated using an automated method for hydroperoxide estimation in patients with coronary artery disease

Background: Reactive oxygen species (ROS) play a major role in the pathogenesis of different chronic and degenerative diseases, including atherosclerosis...

Keywords: atherosclerosis, coronary artery disease, diabetes, hydroperoxides, oxidative stress, risk factors

03/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Computerized cardiotocography parameters in pregnant women affected by pregestational diabetes mellitus

Aim: To evaluate whether computerized CTG (cCTG) is a reliable method of predicting neonatal outcome in pregnancies complicated by pregestational diabetes at term.

Patients and methods: We considered 27 pregnant women affected by pregestational diabetes and 46 normal pregnancies as controls that fulfilled the following criteria: singleton, Caucasian, euglycemic pregnancies at term (>37 weeks gestational age)...

Keywords: Computerized CTG, diabetes, fetal acidemia, umbilical blood gas analysis

09/2004 | Journal of Perinatal Medicine, Walter de Gruyter
Structural-tridimensional study of yolk sac in pregnancies complicated by diabetes

Objectives: To assess by two- and three-dimensional ultrasound the diameter and volume of the yolk sac in pregnant women affected by type 1 diabetes during the first trimester of pregnancy.

Methods: 18 women affected by insulin-dependent diabetes mellitus (IDDM) and 52 normoglycemic pregnant women (controls) were enrolled in this study...

Keywords: diabetes, three-dimensional ultrasonography, ultrasound, yolk sac

03/2005 | Journal of Perinatal Medicine, Walter de Gruyter
Structural-tridimensional study of yolk sac in pregnancies complicated by diabetes

Objectives: To assess by two- and three-dimensional ultrasound the diameter and volume of the yolk sac in pregnant women affected by type 1 diabetes during the first trimester of pregnancy.

Methods: 18 women affected by insulin-dependent diabetes mellitus (IDDM) and 52 normoglycemic pregnant women (controls) were enrolled in this study...

Keywords: diabetes, three-dimensional ultrasonography, ultrasound, yolk sac

03/2004 | Journal of Perinatal Medicine, Walter de Gruyter
Placental Doppler velocimetry in gestational diabetes mellitus

Objective: To evaluate if maternal glucose level and growth of the fetus were related to placental vascular impedance in pregnancy complicated by gestational diabetes mellitus.

Material and methods: A retrospective study of 146 gestational diabetic women of which 117 needed insulin therapy...

Keywords: diabetes, Doppler, gestational, pregnancy, uterine artery, umbilical artery

04/2006 | Journal of Perinatal Medicine, Walter de Gruyter
The efficacy of first-trimester PAPP-A and free ?hCG levels for predicting adverse pregnancy outcome

Objective: To determine whether first-trimester measurements of maternal serum PAPP-A and free ?hCG levels were associated with adverse pregnancy outcomes.

Study Design: First trimester maternal serum free ?hCG and PAPP-A were measured in 490 singleton pregnancies...

Keywords: diabetes, hCG, PAPP-A, preeclampsia, pregnancy outcome, screening, SGA

04/2006 | Journal of Perinatal Medicine, Walter de Gruyter
Rapid sample preparation and simultaneous quantitation of prostaglandins and lipoxygenase derived fatty acid metabolites by liquid chromatography-mass spectrometry from small sample volumes

Background: Fatty acid metabolites play a key role in numerous physiological and pathological processes...

Keywords: diabetes, fatty acid metabolites, liquid chromatography-mass spectrometry (LC-MS/MS), lipid oxidation products, prostaglandins

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The entero-insular axis: implications for human metabolism

Incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are intestinal hormones that are released in response to ingestion of nutrients, especially carbohydrate...

Keywords: adipose tissue, ?-cells, bone, brain, diabetes, dipeptidyl peptidase IV (DPPIV), exendin-4, glucagon-like peptide 1 (GLP-1), glucose, glucose-dependent insulinotropic polypeptide (GIP), incretins, insulin, liver, metabolism

01/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
High free serum acrolein levels in bacterial infection and other disease states associated with oxidative stress: a potential biomarker?

No available

Keywords: cerebrovascular accident, cirrhosis, diabetes, myeloperoxidase, oxidative stress, pneumonia, uremia

11/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Monitoring glycaemic control: is there evidence for appropriate use of routine measurement of glycated haemoglobin?

Background: Regardless of the available recommendations to perform glycated haemoglobin testing at a 2- to 3-month frequency, there is increasing evidence of an inappropriate laboratory use of this test in clinical practice.

Methods: Data from our Laboratory Information System were analysed for glycated haemoglobin test orders over a 3-year period using Microsoft® Excel to calculate the order intervals and the test frequency for each patient...

Keywords: Appropriateness, diabetes, glycosylated haemoglobin, laboratory testing, monitoring

08/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group

The measurement of glycated hemoglobin is central in the monitoring of glycemic control in patients with diabetes...

Keywords: diabetes, glycated hemoglobin, HbA1c, network, reference methods, standardization

08/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
On the independence of intraindividual reference values

No available

Keywords: correlations, diabetes, steady state

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter