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Items for "dexamethasone"

Glucocorticoid receptor-mediated expression of kallikrein 10 in human breast cancer cell lines

Using the breast cell lines MCF-10A, MDA-MB-468 and T-47D, we investigated the role of various glucocorticoids in regulating human kallikrein 10 expression...

Keywords: betamethasone, cell culture, dexamethasone, differential regulation, Mifepristone, steroid hormones

10/2007 | Biological Chemistry, Walter de Gruyter
Below median birth weight in appropriate-for-gestational-age preterm infants as a risk factor for bronchopulmonary dysplasia

Aims: To assess the presence of chorioamnionitis and intrauterine growth as prenatal risk factors for broncho pulmonary dysplasia (BPD) in appropriate-for-gestational-age (AGA) infants of <28 weeks' gestation.

Methods: Gender, race, birth weight, gestational age, histology of the placenta, diagnosis of BPD at 36 weeks' gestation, postnatal dexamethasone treatment, and death were recorded in 150 preterm infants born at <28 weeks' gestation, and admitted between 1996 and 2001.

Results: In 122 AGA infants (mean gestational age: 26.18 weeks, mean birth weight: 837 g), BPD was associated with gestational age-related birth weights below the 50th centile...

Keywords: Appropriate-for-gestational-age, broncho-pulmonary dysplasia, Chorioamnionitis, dexamethasone, extremly-low-birth-weight infants, intrauterine growth, intrauterine infection, placenta histology, preterm infants

07/2008 | Journal of Perinatal Medicine, Walter de Gruyter