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Items for "dermatan sulfate"

Alterations in serum glycosaminoglycan profiles in Graves' patients

Background: Qualitative and quantitative analyses of glycosaminoglycans (GAGs) in serum obtained from Graves' disease (GD) patients without extrathyroidal complications were carried out to provide a clearer understanding of the role of these macromolecules in the disease pathogenesis.

Methods: GAGs were isolated from serum of 17 GD patients before treatment and after attainment of the euthyroid state, as well as from 20 healthy individuals...

Keywords: chondroitin sulfate, dermatan sulfate, Glycosaminoglycans, heparan sulfate/heparin

05/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Age-related changes of plasma glycosaminoglycans

Background: This study was undertaken to reveal how the physiological ageing process influences plasma glycosaminoglycans (GAGs) content and composition.

Methods: GAGs isolated from plasma samples obtained from 105 healthy subjects were quantified using a hexuronic acid assay and subjected to electrophoretic fractionation.

Results: We found that total GAGs decreased gradually with advancing age...

Keywords: ageing process, chondroitin sulfate, dermatan sulfate, extracellular matrix, heparin sulfate/heparin, plasma glycosaminoglycans

10/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter