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Items for "dementia"

Electrophoretic separations of cerebrospinal fluid proteins in clinical investigations

The cerebrospinal fluid (CSF) is a key sample in the research for novel molecular biomarkers of neurodegenerative disorders...

Keywords: cerebrospinal fluid, 2-D electrophoresis, dementia, proteomics, matrix assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF-MS), neurodegeneration

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Detection of brain injury by fatty acid-binding proteins

The rapid detection of brain injury (neuronal damage in general) is an important parameter in the management of cerebrovascular accidents, especially in hemorrhagic and/or ischemic events...

Keywords: brain injury, dementia, fatty acid-binding protein, heart-type fatty acid-binding protein (H-FABP), Ischemia, neurological disorders, Stroke

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Homocysteine in relation to cognitive performance in pathological and non-pathological conditions

Elevated serum homocysteine has been associated with increased risk of Alzheimer's disease...

Keywords: aging, cognition, dementia, homocysteine, multiple sclerosis

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Homocysteine and B vitamins in mild cognitive impairment and dementia

Elderly subjects with mild cognitive impairment have a high risk for conversion to Alzheimer's disease or are already in a preclinical dementia stage...

Keywords: dementia, folate, homocysteine, mild cognitive impairment, vitamin B12

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Plasma homocysteine levels in L-dopa-treated Parkinson's disease patients with cognitive dysfunctions

Elevated plasma homocysteine (Hcy) concentrations are associated with Alzheimer's disease and vascular dementia...

Keywords: cognitive dysfunctions, dementia, homocysteine, L-dopa

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Analytical performance and clinical utility of the INNOTEST® PHOSPHO-TAU(181P) assay for discrimination between Alzheimer's disease and dementia with Lewy bodies

Background: Total tau (T-tau) and ?-amyloid(1-42) (A?1-42) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia...

Keywords: cerebrospinal fluid, dementia, diagnosis, performance, P-tau181P

12/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter