P-selectin inhibition has been shown to decrease thrombogenesis in multiple animal species. In this study, we show that a novel oral small-molecule inhibitor of P-selectin, PSI-697, promotes thrombus resolution and decreases inflammation in a baboon model of venous thrombosis...
Keywords: Deep venous thrombosis, thrombus resolution, small-molecule inhibitor of p-selectin, inflammation, Animal models
03/2007 | Thrombosis and Haemostasis, SchattauerPlasma homocysteine was assessed in Behçet's disease (BD) patients in order to determine the prevalence of hyperhomocysteinaemia in BD and to test its association with clinical manifestations of the disease...
Keywords: Deep venous thrombosis, endothelial dysfunction, homocysteine, oxidant stress, retinal vasculitis, uveitis
12/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter