Items for "de-ubiquitination"

Josephin domain-containing proteins from a variety of species are active de-ubiquitination enzymes

The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3) is caused by the presence of an extended polyglutamine stretch (polyQ) in the unstructured C-terminus of the human ataxin-3 (AT3) protein...

Keywords: Ataxin-3, de-ubiquitination, neurodegenerative diseases, polyglutamine proteins, protein misfolding