Items for "D-dimer"

Simple and safe exclusion of pulmonary embolism in outpatients using quantitative D-dimer and Wells' simplified decision rule

A safe and effective management strategy is pivotal in excluding pulmonary embolism (PE). The combination of Wells' simplified dichotomous clinical decision rule and D-dimer test is non-invasive and could be highly efficient, though its safety has not been widely studied...

Keywords: Clinical studies, pulmonary embolism, diagnosis management, D-dimer, clinical decision rule

A model for the harmonisation of test results of different quantitative D-dimer methods

The numerical test results of different D-dimer assays vary widely. Because of the complexity of the analyte of target as well as the variability in specificity of different D-dimer assays, only harmonisation of the test results seems to be feasible...

Keywords: D-dimer, harmonisation, linear regression, commutability

Sensitivity and specificity of a quantitative point of care D-dimer assay using heparinized whole blood, in patients with clinically suspected deep vein thrombosis

D-dimer assays are efficient in the exclusion diagnostics of deep vein thrombosis (DVT) in patients without severe concomitant diseases...

Keywords: deep vein thrombosis, D-dimer, point-of-care assay

Evaluation of pre-analytical, demographic, behavioural and metabolic variables on fibrinolysis and haemostasis activation markers utilised to assess hypercoagulability

Background: Measurement of some haemostatic factors and products formed during activation of haemostasis seems to be promising in the determination of hypercoagulability.

Methods: The fibrinolytic variables euglobulin clot lysis time, tissue-type plasminogen activator, plasminogen activator inhibitor-1 and the haemostasis activation markers prothrombin fragment 1+2, thrombin-antithrombin complex and D-dimer were determined in 101 apparently healthy men and women aged 20–92 years (58±18 years, mean±SD) to establish variability due to several demographic, behavioural and metabolic factors.

Results: None of the fibrinolytic variables were affected by smoking, while tissue-type plasminogen activator antigen was significantly lower in women compared to men...

Keywords: D-dimer, fibrinolysis, plasminogen activator inhibitor-1, prothrombin fragment 1+2, thrombin-antithrombin complex, Tissue-type plasminogen activator

The new role of D-dimer as a predictor of recurrent venous thromboembolism D-Dimere: Ihre neue Rolle als Prädiktoren für rezidivierende venöse Thromboembolien

Venous thromboembolism (VTE) tends to recur after oral anticoagulant therapy (OAT) withdrawal, regardless of the duration of treatment...

Keywords: D-Dimer, Fibrin-Fibrinogen-Degradationsprodukte, orale Antikoagulanzien, Risikofaktoren, venöse Thromboembolie