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Items for "cysteine protease inhibitors"

The staphostatin family of cysteine protease inhibitors in the genus Staphylococcus as an example of parallel evolution of protease and inhibitor specificity

Staphostatins constitute a family of staphylococcal cysteine protease inhibitors sharing a lipocalin-like fold and a unique mechanism of action...

Keywords: cysteine protease inhibitors, cysteine proteases, regulation of proteolysis, staphostatins, staphylococci

02/2007 | Biological Chemistry, Walter de Gruyter
Cysteine protease inhibitors effectively reduce in vivo levels of brain ?-amyloid related to Alzheimer's disease

Abnormal accumulation of neurotoxic ?-amyloid peptides (A?) in brain represents a key factor in the progression of Alzheimer's disease (AD)...

Keywords: APP processing, ?-amyloid, brain, cysteine protease inhibitors, in vivo administration

02/2007 | Biological Chemistry, Walter de Gruyter