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cysteine cathepsins
Items for "cysteine cathepsins"
Cysteine cathepsins in human cancer
Proteases play causal roles in the malignant progression of human tumors. This review centers on the roles in this process of cysteine cathepsins, i.e., peptidases belonging to the papain family (C1) of the CA clan of cysteine proteases...
Keywords: breast carcinoma, cathepsin B, colorectal carcinoma, cystatins, cysteine cathepsins, glioblastoma, melanoma, prostate carcinoma
11/2004 | Biological Chemistry, Walter de GruyterDegradation of apolipoprotein B-100 by lysosomal cysteine cathepsins
Although the degradation of cellular or endocytosed proteins comprises the normal function of lysosomal proteinases, these enzymes were also detected extracellularly during diseases such as atherosclerosis...
Keywords: apolipoprotein B-100, cell-associated proteolysis, cleavage sites, cysteine cathepsins, LDL particle fusion, N-terminal sequencing
09/2006 | Biological Chemistry, Walter de GruyterCathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen
Cathepsin V is a lysosomal cysteine peptidase highly expressed in corneal epithelium; however, its function in the eye is still unknown...
Keywords: Angiogenesis, Angiostatin, corneal epithelium, cysteine cathepsins, plasminogen
02/2008 | Biological Chemistry, Walter de Gruyter