Proteases play causal roles in the malignant progression of human tumors. This review centers on the roles in this process of cysteine cathepsins, i.e., peptidases belonging to the papain family (C1) of the CA clan of cysteine proteases...
Keywords: breast carcinoma, cathepsin B, colorectal carcinoma, cystatins, cysteine cathepsins, glioblastoma, melanoma, prostate carcinoma
11/2004 | Biological Chemistry, Walter de GruyterCysteine proteases (cathepsins) play a pivotal role in various physiological processes, as well as in several diseases...
Keywords: antigen presentation, asparagine endopeptidase, autophagy, cathepsins, cystatins, dipeptidyl peptidase I
11/2007 | Biological Chemistry, Walter de Gruyter