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Items for "cystatin C"

Detection of impaired renal function: Is the modern serologic marker cystatin C more accurate than the 99mTc-MAG3 clearance

Aim: Renal function is usually determined by means of creatinine-clearance, and of serum Cystatin C, the latter with increasing frequency...

Keywords: Kreatinin-Clearance, Cystatin C, 99mTc-MAG3 Clearance

01/2004 | Nuklearmedizin, Schattauer
The efficacy of cystatin C assay in the prediction of glomerular filtration rate. Is it a more reliable marker for renal failure?

We determined the sensitivity, specificity, receiver operating characteristics and correlation between cystatin C (cysC) and two widely used markers of renal function, creatinine clearance and serum creatinine, in 244 patients (84 diabetics, 84 hypertensive and 76 healthy subjects)...

Keywords: creatinine, cystatin C, diabetes, glomerular filtration rate (GFR), hypertension

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Renal function – estimation of glomerular filtration rate

Assessment and follow-up of renal dysfunction is important in the early detection and management of chronic kidney disease...

Keywords: Cockcroft-Gault formula, creatinine, cystatin C, glomerular filtration rate, MDRD (Modification of Diet in Renal Disease) study equation, renal function

11/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Variations in assay protocol for the Dako cystatin C method may change patient results by 50% without changing the results for controls

Background: Cystatin C is increasingly used as a glomerular filtration marker, but so far only a few companies produce most of the cystatin C reagents suited for turbidimetry or nephelometry use in clinical laboratories.

Methods: We studied different protocols for measuring cystatin C on an Architect ci8200 system using cystatin C reagents from Dako (Glostrup, Denmark)...

Keywords: cystatin C, erroneous results, glomerular filtration ratio, immunoassay, Kidney function, recombinant proteins, turbidimetry

12/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Urinary cystatin C as a specific marker of tubular dysfunction

Background: Cystatin C (CST3), a strong inhibitor of cysteine proteinases, is freely filtered by the kidney glomerulus and is reabsorbed by the tubules, where it is almost totally catabolized, with the remainder then eliminated in urine...

Keywords: cystatin C, kidney, tubular marker, tubulopathy, urine

03/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Hepatorenal syndrome

This article summarizes the literature on current definition, suggested pathogenetic mechanisms and the role of laboratory assessment in the differential diagnosis of hepatorenal syndrome (HRS) from other causes of renal disease that may arise during hepatic cirrhosis and some diseases affecting both liver and kidney...

Keywords: cystatin C, hepatorenal syndrome, laboratory assessment

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
MDRD-Formel und Cystatin C. Verbesserungen zur Erfassung der glomerulären Filtrationsrate? MDRD formula and cystatin C. Improvements in the assessment of the glomerular filtration rate?

Zusammenfassung

Die Bestimmung von Kreatinin im Serum oder Plasma zur Erfassung einer verminderten glomerulären Filtrationsrate (GFR) stellt zum jetzigen Zeitpunkt einen Standard im medizinischen Alltag dar...

Keywords: cystatin C, Glomeruläre Filtrationsrate (GFR), Kreatinin, MDRD-Formel, creatinine, glomerular filtration rate (GFR), MDRD formula

07/2005 | LaboratoriumsMedizin, Walter de Gruyter
Hepatorenal syndrome

This article summarizes the literature on current definition, suggested pathogenetic mechanisms and the role of laboratory assessment in the differential diagnosis of hepatorenal syndrome (HRS) from other causes of renal disease that may arise during hepatic cirrhosis and some diseases affecting both liver and kidney...

Keywords: Cystatin C, Hepatorenales Syndrom, Labortests

10/2006 | LaboratoriumsMedizin, Walter de Gruyter
A new serum cystatin C-based equation for assessing glomerular filtration rate in liver transplantation

Background: Cystatin C (CysC) has been identified to be an alternative marker of glomerular filtration rate (GFR), but no CysC-based equation has been developed for patients receiving liver transplantation.

Methods: Serum CysC and 99mTc-DTPA clearance (true GFR) were measured simultaneously on post-transplant days 1, 4 and 7...

Keywords: Bland and Altman analysis, cystatin C, DTPA clearance, glomerular filtration rate, Liver transplantation

03/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Intra-individual variation in creatinine and cystatin C

Background: Serum creatinine and cystatin C are measured in the assessment of glomerular filtration rate...

Keywords: creatinine, cystatin C, glomerular filtration rate, intra-individual variation

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Sources of variation and reference intervals for serum cystatin C in a healthy Japanese adult population

Background: To derive reference intervals (RIs) for cystatin C (CysC), we examined sources of variation in its serum concentration by multiple regression analysis.

Methods: A total of 596 healthy subjects (30–75 years of age) who underwent an annual health check were chosen as candidate reference individuals who did not have any chronic illness requiring medication...

Keywords: age-related change, cystatin C, latent abnormal values exclusion method, multiple regression analysis, preanalytical variation

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Is cystatin C a reliable renal marker in trauma?

No available

Keywords: cystatin C, trauma

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Reference intervals for serum cystatin C in healthy Mexican adults

No available

Keywords: cystatin C, creatinine, glomerular filtration rate (GFR), reference intervals, renal function

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter