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Items for "cruzipain"

Kunitz-type Bauhinia bauhinioides inhibitors devoid of disulfide bridges: isolation of the cDNAs, heterologous expression and structural studies

Bauhinia bauhinoides cruzipain inhibitor (BbCI) and Bauhinia bauhinioides kallikrein inhibitor (BbKI) are cysteine and serine proteinase inhibitors structurally homologous to plant Kunitz-type inhibitors, but are devoid of disulfide bridges...

Keywords: cathepsins, cruzipain, elastase, gene, kallikreins, proteinase inhibitors

06/2005 | Biological Chemistry, Walter de Gruyter
Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway

Tissue injury by pathogens induces a stereotyped inflammatory response that alerts the innate immune system of the potential threat to host integrity...

Keywords: angiotensin, bradykinin, cruzipain, dendritic cells, Trypanosoma cruzi

08/2008 | Biological Chemistry, Walter de Gruyter