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Items for "cross-talk"

GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways

The epidermal growth factor receptor (EGFR) plays a key role in the regulation of important cellular processes under normal and pathophysiological conditions such as cancer...

Keywords: ADAM, breast cancer, cross-talk, HB-EGF, shedding, sphingosine kinase (SPHK)

09/2005 | Biological Chemistry, Walter de Gruyter
Modulation of autocrine TNF-?-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogen-activated protein kinases in THP-1 monocytic cells

Matrix metalloproteinase 9 (MMP-9) is implicated in various physiological processes by its ability to degrade the extracellular matrix (ECM) and process multiple regulatory proteins...

Keywords: cross-talk, ERK, gelatinase B, JNK, leukemia, p38

01/2006 | Biological Chemistry, Walter de Gruyter