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Items for "creatinine"

New creatinine sensor for point-of-care testing of creatinine meets the National Kidney Disease Education Program guidelines

Addition of the measurement of creatinine concentration in whole blood on the ABL837 FLEX blood gas analyzer (Radiometer Medical ApS, Copenhagen, Denmark) allows fast and reliable reporting of creatinine in point-of-care testing (POCT)...

Keywords: creatinine, glomerular filtration rate (GFR), National Kidney Disease Education Program (NKDEP) standardization, point-of-care testing

01/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Quality of serum creatinine measurement in light of EQA programs

Background: The aim of our study was to identify the role of External Quality Assessment (EQA) programs in improving the quality of serum creatinine measurement and glomerular filtration rate (GFR) estimation...

Keywords: bias, creatinine, External Quality Assessment (EQA), glomerular filtration rate, kidney

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Effects of analytic variations in creatinine measurements on the classification of renal disease using estimated glomerular filtration rate (eGFR)

Background: This study uses the Isotope Dilution Mass Spectrometer-Traceable Modification of Diet in Renal Disease (MDRD) equation to evaluate the effects of analytic variation of serum creatinine on estimated glomerular filtration rate (eGFR)...

Keywords: bias, creatinine, estimated GFR (eGFR), glomerular filtration (GFR), Guidelines

06/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The efficacy of cystatin C assay in the prediction of glomerular filtration rate. Is it a more reliable marker for renal failure?

We determined the sensitivity, specificity, receiver operating characteristics and correlation between cystatin C (cysC) and two widely used markers of renal function, creatinine clearance and serum creatinine, in 244 patients (84 diabetics, 84 hypertensive and 76 healthy subjects)...

Keywords: creatinine, cystatin C, diabetes, glomerular filtration rate (GFR), hypertension

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Impact of standardized calibration on the inter-assay variation of 14 automated assays for the measurement of creatinine in human serum

Purpose: The aim of our study was to measure the inter-assay variation and accuracy of serum creatinine assays and to assess the effect of standardized calibration procedures on this variability...

Keywords: compensated Jaffe technique, creatinine, enzymatic techniques, glomerular filtration rate, inter-laboratory imprecision, Jaffe techniques

11/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Comparison between creatinine and pregnanediol adjustments in the retrospective analysis of urinary hormone profiles during the human menstrual cycle

Measurement of reproductive hormones in urine is a practical way of obtaining large amounts of information; however, there is still controversy on how to overcome problems derived from volume fluctuations between samples...

Keywords: creatinine, luteinizing hormone, menstrual cycle, pregnanediol, steroids

09/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The importance of metrological traceability on the validity of creatinine measurement as an index of renal function: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)

The glomerular filtration rate (GFR) is currently considered the best overall index of kidney function...

Keywords: calibration, creatinine, glomerular filtration rate, kidney function tests, reference standards, traceability

10/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Renal function – estimation of glomerular filtration rate

Assessment and follow-up of renal dysfunction is important in the early detection and management of chronic kidney disease...

Keywords: Cockcroft-Gault formula, creatinine, cystatin C, glomerular filtration rate, MDRD (Modification of Diet in Renal Disease) study equation, renal function

11/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Relationship between serum uric acid, creatinine, albumin and gestational diabetes mellitus

Background: During normal pregnancy, plasma concentrations of creatinine and uric acid normally decrease as a consequence of their increased glomerular filtration...

Keywords: Albumin, creatinine, gestational diabetes, uric acid

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
MDRD-Formel und Cystatin C. Verbesserungen zur Erfassung der glomerulären Filtrationsrate? MDRD formula and cystatin C. Improvements in the assessment of the glomerular filtration rate?

Zusammenfassung

Die Bestimmung von Kreatinin im Serum oder Plasma zur Erfassung einer verminderten glomerulären Filtrationsrate (GFR) stellt zum jetzigen Zeitpunkt einen Standard im medizinischen Alltag dar...

Keywords: cystatin C, Glomeruläre Filtrationsrate (GFR), Kreatinin, MDRD-Formel, creatinine, glomerular filtration rate (GFR), MDRD formula

07/2005 | LaboratoriumsMedizin, Walter de Gruyter
Trueness verification of actual creatinine assays in the European market demonstrates a disappointing variability that needs substantial improvement. An international study in the framework of the EC4 creatinine standardization working group

Background: The European In Vitro Diagnostics (IVD) directive requires traceability to reference methods and materials of analytes...

Keywords: analytical error, bias, calibration, creatinine, External Quality Assessment, glomerular filtration rate, reference methods

09/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Modeling the variability of creatinine measurements improves estimates of the glomerular filtration rate

Background: The precision of the formulae used to estimate glomerular filtration rate (GFR) decreases when the serum creatinine (SCr) assay is biased compared with the assay used during the development of the formulae.

Methods: For 100 children referred for 51Cr-EDTA clearance (CLEDTA), SCr was measured with a JAFFE (classic Jaffe colorimetric creatinine assay), a compensated Jaffe (COMP), an enzymatic (ENZ) and an HPLC assay...

Keywords: creatinine, modeling, population pharmacokinetics, standardization

10/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Comparison of creatinine-based estimations of glomerular filtration rate in endurance athletes at rest

Background: Several creatinine-based estimates of the glomerular filtration rate (GFR) have been advocated as reliable alternatives to the urinary clearance of exogenous filtration markers...

Keywords: creatinine, glomerular filtration rate, glomerular function rate, Modification of Diet in Renal Disease (MDRD), sport

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Point-of-care creatinine testing in children at risk for sudden deterioration of renal function

Background: Point-of-care testing for creatinine blood concentrations may be useful in predicting the onset of recurrent conditions threatening renal function in children at home...

Keywords: child, creatinine, haemolytic-uremic syndrome, physiological monitoring, point-of-care systems

11/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Intra-individual variation in creatinine and cystatin C

Background: Serum creatinine and cystatin C are measured in the assessment of glomerular filtration rate...

Keywords: creatinine, cystatin C, glomerular filtration rate, intra-individual variation

09/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Reference intervals for serum cystatin C in healthy Mexican adults

No available

Keywords: cystatin C, creatinine, glomerular filtration rate (GFR), reference intervals, renal function

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter