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Items for "Coronary disease"

Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: The Rotterdam Study

Fibrin network structure has been correlated with coronary disease. Fibrinogen and (FGG and FGA) gene haplotypes (chromosome 4q28) may be associated with fibrin network structure, and thereby with rigidity of the fibrin clot and sensitivity of the fibrin clot to the fibrinolytic system...

Keywords: Coronary disease, atherosclerosis, epidemiology, genetics, fibrinogen

00/0000 | Thrombosis and Haemostasis, Schattauer

Factor XIII Val34Leu variant protects against coronary artery disease. A meta-analysis

Several studies suggested that Val34Leu variant of factor XIII (FXIII) might have a protective effect against coronary artery disease (CAD), but studies not supporting these findings have also been published...

Keywords: Coronary disease, factor XIII, Polymorphism, meta-analysis

03/2007 | Thrombosis and Haemostasis, Schattauer

Potent arterial antithrombotic effect of direct factor-Xa inhibition with ZK-807834 administered to coronary artery disease patients

It was the objective of this study to evaluate the anti-thrombotic potency of direct factor-Xa inhibition with ZK-807834 in stable coronary patients, using an ex-vivo model of arterial thrombus formation...