Items for "coronary artery disease"

SPECT myocardial perfusion imaging: Long-term prognostic value in diabetic patients with and without coronary artery disease

Aim: To determine the long-term prognostic value of SPECT myocardial perfusion imaging (MPI) for the occurrence of cardiovascular events in diabetic patients...

Keywords: Diabetes mellitus, koronare Herzkrankheit, Myokardischämie, Prognose; Myokardperfusion, SPECT

Combined use of 64-slice computed tomography angiography and gated myocardial perfusion SPECT for the detection of functionally relevant coronary artery stenoses First results in a clinical setting concerning patients with stable angina

AIM: In patients with stable angina pectoris both morphological and functional information about the coronary artery tree should be present before revascularization therapy is performed...

Keywords: Myokardszintigraphie, SPECT, 64-Zeilen-CT-Angiographie, invasive Koronarangiographie, koronare Herzerkrankung, stabile Angina pectoris

The 11377 C > G promoter variant of the adiponectin gene, prevalence of coronary atherosclerosis, and incidence of vascular events in men

No prospective data demonstrating an association between the 11377 C > G adiponectin gene promoter variant and cardiovascular risk are available...

Keywords: coronary artery disease, angiography, risk factors, cytokines, epidemiology

Paraoxonase 1 gene polymorphisms in angiographically assessed coronary artery disease: evidence for gender interaction among Brazilians

Background: Paraoxonases (PON) are members of an enzyme family involved in preventing low-density lipoprotein oxidation and therefore protecting against atherosclerotic plaque formation.

Methods: We studied the Met55Leu and Gln192Arg PON1 polymorphisms in 712 patients (437 Caucasian- and 275 African-Brazilians) who underwent coronary angiography.

Results: Among Caucasian-Brazilians, the homozygous 55LeuLeu frequency was higher among patients with significant coronary artery disease (CAD, obstructive lesions ?50%) than among lesion-free controls (51% vs...

Keywords: African-Brazilians, coronary artery disease, paraoxonase, Polymorphism

Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis

Antibody titer against malondialdehyde (MDA)-modified low-density lipoprotein (LDL) has been found to be associated with atherosclerosis, but it has not been established whether it would detect subjects with coronary artery disease (CAD)...

Keywords: antibodies, coronary artery disease, high-density lipoprotein cholesterol, malondialdehyde-modified low-density lipoprotein, receiver-operating characteristic analysis

The ratio of apoB/apoAI, apoB and lipoprotein(a) are the best predictors of stable coronary artery disease

Background: The ratio of low- to high-density lipoprotein-cholesterol (LDL-C/HDL-C) conventionally represents the balance of proatherogenic and anti-atherogenic lipids...

Keywords: apolipoprotein (apo), apoB/apoAI ratio, cholesterol, coronary artery disease, lipoprotein(a)

Asymmetrisches Dimethylarginin (ADMA): ein neuer Marker zur Abschtzung des kardiovaskulren Risikos / Asymmetric dimethyl arginine (ADMA): a new marker for evaluating cardiovascular risk

Zusammenfassung Asymmetrisches Dimethylarginin (ADMA) ist eine endogen produzierte Aminosure, die alle drei Isoformen der Stickoxid-Synthase inhibiert...

Keywords: Asymmetrisches Dimethylarginin (ADMA), Atherosklerose, biomarker, endotheliale Dysfunktion, kardiovaskulres Risiko, Stickstoffmonoxid, atherosclerosis, aymmetric dimethyl arginine (ADMA), cardiovascular risk, coronary artery disease, endothelial dysfunction, nitric oxide

The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis

Background: Angiotensin II is produced primarily by angiotensin I-converting enzyme (ACE) within atherosclerotic lesions and ACE level in plaques correlates with the severity of vessel wall damage...

Keywords: angiotensin I-converting enzyme gene (ACE), atherosclerosis, coronary artery disease, Polymorphism

Interactions of lipoprotein(a) with diabetes mellitus, apolipoprotein B and cholesterol enhance the prognostic values for coronary artery disease

Background: Synergistic interactions between elevated serum lipoprotein(a) [Lp(a)] and other unfavorable risk factors have been proposed to cause very high risk for coronary artery disease (CAD)...

Keywords: apolipoprotein B, cholesterol, coronary artery disease, Diabetes mellitus, lipoprotein(a)

Homocysteine, left ventricular dysfunction and coronary artery disease: is there a link?

Experimental and observational studies support a role of plasma homocysteine levels (tHcy) in coronary artery disease (CAD)...

Keywords: cardiac dysfunction, coronary artery disease, homocysteine

The ?374A allele of the receptor for advanced glycation end products (RAGE) gene promoter is a protective factor against cardiovascular lesions in type 2 diabetes mellitus patients

Background: Polymorphisms of the receptor for advanced glycation end products (RAGE) gene have been associated with diabetes, coronary artery disease (CAD) and inflammatory processes...

Keywords: advanced glycation end products, coronary artery disease, disease severity, Euro-Brazilians, risk factor, single nucleotide polymorphism, type 2 diabetes