Items for "connexin-43"

Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells

Exposure of rat liver epithelial cells to doxorubicin, an anthraquinone derivative widely employed in cancer chemotherapy, led to a dose-dependent decrease in gap junctional intercellular communication (GJC)...

Keywords: connexin-43, extracellular signal-regulated kinase (ERK), gap junction, mitogen-activated protein (MAP) kinase, oxidative stress, signal transduction, stress signaling