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Items for "commutability"

A model for the harmonisation of test results of different quantitative D-dimer methods

The numerical test results of different D-dimer assays vary widely. Because of the complexity of the analyte of target as well as the variability in specificity of different D-dimer assays, only harmonisation of the test results seems to be feasible...

Keywords: D-dimer, harmonisation, linear regression, commutability

03/2006 | Thrombosis and Haemostasis, Schattauer

A reference material for traceability of aspartate aminotransferase (AST) results

Standardization of aspartate aminotransferase (AST) determination is highly desirable for inter-laboratory comparison...

Keywords: commutability, enzyme calibrator, metrological traceability, reference material, reference measurement procedure

05/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

External Quality Assessment in The Netherlands: time to introduce commutable survey specimens. Lessons from the Dutch “Calibration 2000” project

The performance of suitable secondary reference material for the use of trueness control of six routinely measured clinical enzymes in the Dutch External Quality Assessment (EQA) scheme is described...

Keywords: calibration, commutability, enzyme activity, External Quality Assessment, reference materials

03/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Metrological traceability of values for catalytic concentration of enzymes assigned to a calibration material

Background: The metrological traceability of values for the catalytic concentration of several enzymes assigned to a calibration material has been assured by following the recently published International Standard ISO 18153.

Methods: A traceable value with a measurement uncertainty was assigned for the catalytic concentration of alanine aminotransferase, creatine kinase, ?-glutamyltransferase and lactate dehydrogenase in two materials from different sources...

Keywords: commercial calibrator, commutability, enzymes, metrological traceability, primary calibrator

03/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Intermethod calibration of alanine aminotransferase (ALT) and ?-glutamyltransferase (GGT) results: application to Fibrotest^® and Actitest^® scores

Two multi-component scores (Fibrotest^® and Actitest^®) have been proposed to evaluate liver fibrosis or necro-inflammatory lesions as an alternative to liver biopsy...

Keywords: commutability, enzyme calibrator, reference measurement procedure

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Standardization of troponin I measurements: an update

Standardization of cardiac troponin I (cTnI) measurement is important because of the central role for diagnosis of myocardial infarction...

Keywords: calibration, commutability, reference material, traceability, troponin I

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Automated immunoassay methods for ferritin: recovery studies to assess traceability to an international standard

Background: Ferritin standardisation is problematical due to the heterogeneity of ferritin isoforms and the antibodies used in its immunoassay, and the lack of a reference measurement procedure...

Keywords: commutability, comparability, serum ferritin, standardisation of immunoassays, traceability

10/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

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