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Items for "cobalamin"

A simple high-throughput method for the determination of plasma methylmalonic acid by liquid chromatography-tandem mass spectrometry

Background: Cobalamin (Cbl) deficiency is a common clinical phenomenon, in particular among the elderly and possibly also among infants...

Keywords: cobalamin, homocysteine, liquid chromatography-electrospray ionization tandem mass spectrometry, methylmalonic acid (MMA), vitamin B12

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Autoantibodies against intrinsic factor (IF) measured with an ELISA using recombinant human IF as both catching and detecting reagent

The aim was to develop and validate an assay for measuring autoantibodies against human intrinsic factor (IF)...

Keywords: autoimmune disease, blocking antibodies, cobalamin, non-blocking antibodies, pernicious anaemia

04/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Haptocorrin in humans

Background: Evolutionary haptocorrin is the youngest of the cobalamin-binding proteins...

Keywords: analogues, cobalamin, extra cellular fluids, foetal, immunohistochemistry

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Biomarkers of folate and vitamin B12 status in cerebrospinal fluid

Folate and vitamin B12 are essential cofactors for the methionine/homocysteine cycle in the brain...

Keywords: cobalamin, folate, homocysteine, methyl

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Holotranscobalamin in laboratory diagnosis of cobalamin deficiency compared to total cobalamin and methylmalonic acid

Background: Cobalamin-saturated transcobalamin, also called holotranscobalamin (holoTC), constitutes only between 6% and 20% of total plasma B12...

Keywords: cobalamin, holotranscobalamin, methylmalonic acid, renal function

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Management of L-Dopa related hyperhomocysteinemia: catechol-O-methyltransferase (COMT) inhibitors or B vitamins? Results from a review

In recent years, L-Dopa treatment has been indicated as an acquired cause of hyperhomocysteinemia (HHcy)...

Keywords: cobalamin, entacapone, folate, homocysteine, L-dopa, tolcapone

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter