Items for "coactivator"

GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor

The androgen receptor (AR) mediates transactivation of target genes by acting as a dimer in which its amino-terminal domain (AR-NTD) interacts with its carboxyl-terminal, ligand-binding domain (AR-LBD) (N/C interaction)...

Keywords: androgen receptor, coactivator, dimerization, domain interactions, transactivation, transcription