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Items for "cleavage site"

Type 2N von Willebrand disease due to compound heterozygosity for R854Q and a novel R763G mutation at the cleavage site of von Willebrand factor propeptide

Type 2N von Willebrand disease (VWD) is characterized by a markedly decreased affinity of von Willebrand factor (VWF) for factorVIII (FVIII) and is caused by mutations in the D or D3 domain of mature VWF...

Keywords: von Willebrand factor, von Willebrand disease, mutation, cleavage site

09/2006 | Thrombosis and Haemostasis, Schattauer

Calpain proteolysis of insulin-like growth factor binding protein (IGFBP) -2 and -3, but not of IGFBP-1

Calpains are cytoplasmic Ca²⁺-regulated cysteine proteases that may regulate insulin-like growth factor (IGF)-independent actions of insulin-like growth factor binding proteins (IGFBPs) through IGFBP proteolysis...

Keywords: biosensor analysis, Ca2+ - activation, cleavage site, fragmentation, Kinetics, protease

01/2007 | Biological Chemistry, Walter de Gruyter

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You are here: Home :: Keyword index :: Bre bis com :: classification of monoclonal gammopathies - clinical effectiveness cleavage site

Items for "cleavage site"

Type 2N von Willebrand disease due to compound heterozygosity for R854Q and a novel R763G mutation at the cleavage site of von Willebrand factor propeptide

Calpain proteolysis of insulin-like growth factor binding protein (IGFBP) -2 and -3, but not of IGFBP-1