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Items for "chromatin remodeling"

DNA-binding properties of the recombinant high-mobility-group-like AT-hook-containing region from human BRG1 protein

The hBRG1 protein, a central ATPase of the human switching/sucrose non-fermenting (SWI/SNF) remodeling complex, has a catalytic ATPase domain, an AT-hook motif and a bromodomain...

Keywords: AT-hook, AT-hook-DNA interaction, BRG1, bromodomain, chromatin remodeling, histone acetylation, NMR, SWI/SNF

10/2006 | Biological Chemistry, Walter de Gruyter
Hyperhomocysteinemia, DNA methylation and vascular disease

Hyperhomocysteinemia (HHcy) has been established as a potent independent risk factor for cardiovascular disease (CVD) and the underlying mechanism is largely unknown...

Keywords: atherosclerosis, cardiovascular disease, chromatin remodeling, DNA methylation, endothelial cell growth, homocysteine

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter