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An Educational Intervention, Involving Feedback of Routinely Collected Computer Data, to Improve Cardiovascular Disease Management in UK Primary Care
OBJECTIVES: To report the lessons learned from eight years of feeding back routinely collected cardiovascular data in an educational context METHODS: There are distinct educational and technical components...
Keywords: Computers, ischemic heart disease, quality of healthcare, computerised medical record systems, cholesterol
01/2007 | Methods of Information in Medicine, SchattauerCholesterol is the major component of native lipoproteins activating the p38 mitogen-activated protein kinases
Elevated low-density lipoprotein (LDL) levels induce activation of the p38 mitogen-activated protein kinase (MAPK), a stress-activated protein kinase potentially participating in the development of atherosclerosis...
Keywords: cholesterol, HDL, LDL, lipoproteins, p38 MAPK, signal transduction
09/2005 | Biological Chemistry, Walter de GruyterEvidence supporting the hypothesis that one of the main functions of the aryl hydrocarbon receptor is mediation of cell stress responses
We have previously proposed that one of the major consequences of activation of the aryl hydrocarbon receptor (AhR) by 2,3,7,8-tetrachlorodibenzo-
Keywords: AhR, Apoptosis, cholesterol, IL-8, inflammation, TCDD
09/2006 | Biological Chemistry, Walter de GruyterGhrelin variants influence development of body mass index and plasma levels of total cholesterol in dialyzed patients
Keywords: cholesterol, ghrelin, Polymorphism, renal failure
09/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterDifferentiating transudative from exudative pleural effusion: should we measure effusion cholesterol dehydrogenase?
Keywords: cholesterol, exudate, lactate dehydrogenase (LDH) activity, pleural fluid, total protein, transudate
10/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterInfluence of apolipoprotein E polymorphism on serum lipid and lipoprotein changes: a 21-year follow-up study from childhood to adulthood. The Cardiovascular Risk in Young Finns Study
Keywords: apolipoprotein E polymorphism, cardiovascular risk factors, cholesterol, lipids, long-term follow-up
05/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterCombined transport of water and ions through membrane channels
The coupling of ion and water flow through membrane channels is under dispute. Among all human aquaporins only aquaporin-6 exhibits ion channel activity...
Keywords: cholesterol, cyclic nucleotides, planar membranes, potassium channel, Scanning Electrochemical Microscopy, single file transport
10/2004 | Biological Chemistry, Walter de GruyterPaired helical filaments contain small amounts of cholesterol, phosphatidylcholine and sphingolipids
By using qualitative and quantitative high-performance thin layer chromatography (hpTLC) we found lipids associated with purified Alzheimer's (AD) paired helical filaments (PHF) in an amount of 1.4±0.2% of the total anhydrous mass...
Keywords: amyloid, cholesterol, hpTLC, lipid rafts, paired helical filaments, prion
09/2006 | Biological Chemistry, Walter de GruyterFamilial hypercholesterolemia and response to statin therapy according to
LDLR genetic background
Familial hypercholesterolemia is an autosomal dominant disease defined at the molecular level mainly by the presence of mutations in the low-density lipoprotein receptor gene and is characterized by elevated low-density lipoprotein cholesterol, tendon xanthomas and increased risk of early cardiovascular disease...
Keywords: cholesterol, familial hypercholesterolemia, HMG-CoA, low-density lipoprotein receptor (LDL-R), statins, therapy
08/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterARH missense polymorphisms and plasma cholesterol levels
Mutations in a putative low-density lipoprotein (LDL) receptor adaptor protein called
Keywords: ARH, cholesterol, Polymorphism
09/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterConjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells
Studies in healthy humans have shown that consumption of conjugated linoleic acid (CLA) significantly reduced very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) blood concentrations...
Keywords: apolipoprotein B100 (apoB100), atherosclerosis, cholesterol, conjugated linoleic acid, HepG2 liver cells, lipoprotein
03/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterSerum calcium and phosphorus associate with the occurrence and severity of angiographically documented coronary heart disease, possibly through correlation with atherogenic (apo)lipoproteins
The associations of serum calcium and phosphorus concentrations as well as other cardiovascular risk factors were investigated in relation to the existence and severity of coronary heart disease (CHD) in 260 clinically stable, angiographically defined CHD patients aged 40–70 years...
Keywords: apolipoprotein B, calcium, cholesterol, coronary heart disease, lipoprotein(a), phosphorus
01/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterThe ratio of apoB/apoAI, apoB and lipoprotein(a) are the best predictors of stable coronary artery disease
Keywords: apolipoprotein (apo), apoB/apoAI ratio, cholesterol, coronary artery disease, lipoprotein(a)
08/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterSingle nucleotide polymorphisms in ABCG5 and ABCG8 genes in Chilean subjects with polygenic hypercholesterolemia and controls
Keywords: ABCG5, ABCG8, cholesterol, gene polymorphisms
11/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterVitamin D binding protein, a new nutritional marker in cystic fibrosis patients
Keywords: cholesterol, cystic fibrosis, lipids, nutritional status, Polymorphism, vitamin D binding protein
03/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterEffects of total cholesterol and triglyceride on the percentage difference between the low-density lipoprotein cholesterol concentration measured directly and calculated using the Friedewald formula
Keywords: cholesterol, Friedewald formula, homogeneous method, Koreans, low-density lipoprotein cholesterol
03/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterAre serum lipids measured on stroke admission prognostic?
Keywords: cerebrovascular incident, cholesterol, lipid profile, Prognosis, triglycerides
08/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterInteractions of lipoprotein(a) with diabetes mellitus, apolipoprotein B and cholesterol enhance the prognostic values for coronary artery disease
Keywords: apolipoprotein B, cholesterol, coronary artery disease, Diabetes mellitus, lipoprotein(a)
05/2008 | Clinical Chemical Laboratory Medicine, Walter de GruyterBiomarker bei Sepsis und Entzündung / Biomarkers in Sepsis and Inflammation
Zusammenfassung Schwere systemische Entzündungen wie die Sepsis und der septische Schock stellen die häufigste Todesursache auf der Intensivstation dar...
Keywords: biomarker, Cholesterin, Entzündung, IL-6, PCT, sepsis, Zytokine, cholesterol, cytokines, inflammation
12/2007 | LaboratoriumsMedizin, Walter de Gruyter