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Items for "cancer biomarkers"

Cellular distribution of human tissue kallikreins: immunohistochemical localization

We have studied the immunohistochemical expression (IE) of eight non-tissue-specific human kallikreins (hKs) (hK5, 6, 7, 10, 11, 12, 13, and 14) in different normal tissues...

Keywords: cancer biomarkers, human tissue kallikreins, immunohistochemistry, prognostic markers, serine proteases

06/2006 | Biological Chemistry, Walter de Gruyter
Activation and enzymatic characterization of recombinant human kallikrein 8

Human kallikrein 8 (hK8), whose gene was originally cloned as the human ortholog of a mouse brain protease, is known to be associated with diseases such as ovarian cancer and Alzheimer's disease...

Keywords: cancer biomarkers, human kallikrein 8, human kallikreins, kcat/Km, lysyl endopeptidase, serine protease

06/2006 | Biological Chemistry, Walter de Gruyter
Human tissue kallikrein 9: production of recombinant proteins and specific antibodies

Human tissue kallikreins (genes, KLKs; proteins, hKs) are a subgroup of hormonally regulated serine proteases...

Keywords: antibody generation, cancer biomarkers, human tissue kallikreins, protein expression, protein purification, serine proteases

06/2006 | Biological Chemistry, Walter de Gruyter
Regulation of human tissue kallikrein-related peptidase expression by steroid hormones in 32 cell lines

Human tissue kallikrein-related peptidases (KLK), which are secreted serine proteases, are encoded by 15 genes located on chromosome 19q13.4...

Keywords: cancer biomarkers, cell lines, gene regulation, kallikrein-related peptidases, serine proteases, steroid hormones

11/2008 | Biological Chemistry, Walter de Gruyter
Expression of tissue and plasma kallikreins and kinin B1 and B2 receptors in lung cancer

Tissue kallikrein (hK1) and plasma kallikrein (PK, hKB1) are serine proteases that produce biologically active kinin peptides from endogenous kininogen substrates...

Keywords: cancer biomarkers, kinin B1 and B2 receptors, lung carcinoma subtypes, plasma kallikrein, tissue kallikrein

09/2008 | Biological Chemistry, Walter de Gruyter