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Items for "calpain"

Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain

Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species...

Keywords: calpain, Ca2+-dependent cysteine protease, calpastatin, insulin-like growth factor binding protein

01/2005 | Biological Chemistry, Walter de Gruyter
Digestive versus regulatory proteases: on calpain action in vivo

Calpains, the cytoplasmic Ca2+-activated regulatory proteases, have no simple and clearly definable cleavage site specificity, which is in sharp contrast to digestive (e.g., pancreatic) proteases...

Keywords: calpain, calpastatin, cleavage specificity, enzyme targeting

07/2005 | Biological Chemistry, Walter de Gruyter
Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19INK4d

Calpains are a large family of Ca2+-dependent cysteine proteases that are ubiquitously distributed across most cell types and vertebrate species...

Keywords: calpain, calpastatin, cyclin-dependent kinases, nuclear magnetic resonance spectroscopy, proteolysis, p19INK4d

03/2006 | Biological Chemistry, Walter de Gruyter