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Items for "bradykinin receptor"

Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes

The kinin B2 receptor, which is constitutively expressed in a large number of tissues, mediates most of the known effects of bradykinin (BK)...

Keywords: bradykinin receptor, kidney, knockout mice, microarray

01/2006 | Biological Chemistry, Walter de Gruyter
Generation and characterization of a humanized bradykinin B1 receptor mouse

Antagonists of the B1 bradykinin receptor (B1R), encoded by the BDKRB1 gene, offer the promise of novel therapeutic agents for inflammatory and neuropathic pain...

Keywords: bradykinin receptor, embryonic stem cells, transgenic mouse

02/2006 | Biological Chemistry, Walter de Gruyter
Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system

Bradykinin, a vasoactive peptide, plays a crucial role in many cardiovascular processes via activation of the bradykinin subtype 2 receptor (B2R)...

Keywords: BHK cells, bradykinin receptor, glycosylation, localization, overexpression

05/2006 | Biological Chemistry, Walter de Gruyter