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Items for "blood coagulation"

A potent anti-coagulant RNA aptamer inhibits blood coagulation by specifically blocking the extrinsic clotting pathway

A potent antidote-controlled aptamer, as an anticoagulant, has reportedly overcome the complications of acute bleeding by the administration of available anticoagulants...

Keywords: Aptamer, blood coagulation, extrinsic and intrinsic pathway, inhibition, RNA

05/2006 | Thrombosis and Haemostasis, Schattauer

Identification of a new truncated form and deamidation products of fibrinopeptide B released by thrombin from human fibrinogen

Quantification of fibrinopeptides release is widely used to investigate fibrinogen activation, and standard chromatographic or capillary electrophoretic procedures are readily available...

Keywords: blood coagulation, human, fibrinogen, fibrinopeptides, chromatography, Mass spectrometry

09/2006 | Thrombosis and Haemostasis, Schattauer

Exchange transfusion activates coagulation and alters the coagulation profile in newborn infants

Exchange transfusion (ET) with adult blood is a standard procedure for neonates with severe hyperbilirubinemia...

Keywords: blood coagulation, exchange transfusion, Newborn, Protein C, thrombin

08/2006 | Thrombosis and Haemostasis, Schattauer

Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development

Thrombin is a pivotal enzyme formed in the coagulation cascade and an important and potent platelet activator...

Keywords: blood coagulation, clot elasticity, fibrinolysis, PAR receptors