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Items for "bleeding"

Bleeding after cardiac surgery: the role of recombinant factor VIIa

Cardiac surgery carries a remarkable risk of blood loss requiring transfusion of blood products. Moreover, severe bleeding necessitating reoperation occurs in 35% of patients according to international studies...

Keywords: Herzchirurgie, rFVIIa, Herz-Lungen-Maschine, Blutung

01/2006 | Hämostaseologie, Schattauer

Haemostasis and pregnancy

Normal pregnancy is associated with profound alterations in the coagulation and fibrinolytic systems...

Keywords: haemostasis, Thrombophilia, bleeding, pregnancy

03/2006 | Thrombosis and Haemostasis, Schattauer

Benefit/risk profile of high-dose antithrombin in patients with severe sepsis treated with and without concomitant heparin

A randomised, prospective, placebo-controlled phase III multicentre clinical trial (KyberSept) has been performed to test the efficacy of high-dose antithrombin therapy in patients with severe sepsis...

Keywords: heparin, antithrombin III, severe sepsis, bleeding, survival

05/2006 | Thrombosis and Haemostasis, Schattauer

New concepts in optimal management of anticoagulant therapy for extended treatment of venous thromboembolism

Recent trials on secondary prophylaxis after venous thromboembolism (VTE) have provided a wealth of data on the risk factors for recurrence and, to some extent, also for bleeding...

Keywords: Venous thromboembolism, risk factors, recurrence, bleeding

09/2006 | Thrombosis and Haemostasis, Schattauer

Inhibitors in mild/moderate haemophilia A: An update

The development of inhibitors in patients with mild/moderate hemophilia A is an increasingly recognized occurrence and is manifested by the patients' bleeding pattern becoming more severe...

Keywords: Inhibitors, bleeding, mild hemophilia A

08/2006 | Thrombosis and Haemostasis, Schattauer

Novel molecular defect in the platelet ADP receptor P2Y₁₂ of a patient with haemorrhagic diathesis

Background: The platelet adenosine 5'-diphosphate (ADP) receptor P2Y₁₂ plays a crucial role in haemostasis...

Keywords: adenosine 5?-diphosphate (ADP) receptor, bleeding, mutation, P2Y12, Platelet, thrombus

02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Laboratory diagnosis and clinical manifestations of patients with dysfibrinogenemia / Laboratoriumsdiagnostik und klinische Manifestation der Dysfribrinogenämie

Hereditary dysfibrinogenemia is a rare clotting disorder due to a structural defect in the fibrinogen molecule that results in a tendency for bleeding and thrombosis, as well as obstetric complications...

Keywords: bleeding, dysfibrinogenemia, miscarriage, thrombosis, Abort, Blutung, Dysfibrinogenämia, Thrombose

11/2008 | LaboratoriumsMedizin, Walter de Gruyter

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