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Items for "biometry"

Sample Selection for Microarray Gene Expression Studies

OBJECTIVES: The choice of biomedical samples for microarray gene expression studies is decisive for both validity and interpretability of results...

Keywords: Confounding, Gene expression profiling, biometry, Research design, selection bias, microarray studies

01/2005 | Methods of Information in Medicine, Schattauer
Creative and Innovative Statistics in Clinical Research and Development

Objectives: The aim of this paper is to show that even in a highly regulated area such as clinical research and development in pharmaceutical industry, there are needs and ample opportunities for statisticians and other medical informatics professionals to further creatively develop and implement methods in order to support the collection, analysis and interpretation of clinical data. Methods: The recently published Critical Path initiative of the US Food and Drug Administration discusses the decline in new drug submissions in the last decade and illustrates potential causes in the present clinical development process...

Keywords: Drug evaluation, drug approval, clinical trials, biometry, statistical m

01/2005 | Methods of Information in Medicine, Schattauer
Mean and variance quality control for multiple correlated levels of replicated control samples

Mean and variance rules for quality control are more powerful than rules based on individual values...

Keywords: biometry, clinical chemistry, laboratory techniques and procedures, Quality Control

11/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter