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Items for "biological variation"

Desirable performance standards for HbA1c analysis – precision, accuracy and standardisation Consensus statement of the Australasian Association of Clinical Biochemists (AACB), the Australian Diabetes Society (ADS), the Royal College of P

Background: HbA1c (glycohaemoglobin) is universally used in the ongoing monitoring of all patients with diabetes...

Keywords: accuracy, assay precision, biological variation, glycohaemoglobin, HbA1c, interferences, patient target control ratings, performance standards, standardisation

08/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Biological variation of thyroid autoantibodies and thyroglobulin

Background: It has been shown that the level of serum thyroid antibodies affects serum thyrotropin (TSH) concentrations in men and women, and that these autoantibodies in combination with serum TSH are predictive of future thyroid disease...

Keywords: biological variation, healthy women, thyroglobulin (Tg), thyroglobulin antibodies (TgAb), thyroid peroxidase antibodies (TPOAb), thyrotropin receptor antibodies (TRAb)

08/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Implementing the Stockholm Conference hierarchy of objective quality criteria in a routine laboratory

Background: Analytical performance of clinical laboratory testing should be evaluated against objective quality specifications...

Keywords: biological variation, imprecision, objective, quality, specifications

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The reliability of calculated laboratory results

In clinical laboratories, patient results can be obtained in two ways: (i) by direct determination of requested tests using various chemical methods, (ii) by calculation of unknown test results, based on relationships between measured tests...

Keywords: allowable error, biological variation, coefficient of variation, Levey-Jennings, Quality Control, reliability

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
A new quality control model using performance goals based on biological variation in External Quality Assurance Schemes

A new quality control model using performance goals based on biological variation in External Quality Assurance Schemes (EQAS) is described...

Keywords: biological variation, External Quality Assurance Schemes (EQAS), external quality control, Quality Control

01/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay

The clinical relevance of brain natriuretic peptide (BNP) and N-terminal (NT)-proBNP assays as a diagnostic tool and prognostic marker in patients with cardiovascular diseases has recently been confirmed...

Keywords: Acute coronary syndrome, atrial natriuretic peptide (ANP), biological variation, brain natriuretic peptide (BNP), cardiac function, cardiac natriuretic hormones, cardiovascular diseases, Heart failure

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Analytical quality goals for parathyroid hormone based on biological variation

Background: Measurement of parathyroid hormone (PTH) is central in the investigation of pathologies of bone and mineral ion metabolism...

Keywords: biological variation, laboratory quality specifications, parathyroid hormone, reference change value

10/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter