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Biodistribution
Items for "Biodistribution"
[201Tl](III)-bleomycin for tumor imaging
Due to interesting physical properties and wide availability of thallium-201 as a SPECT radionuclide, the idea of incorporation of this nuclide into biologically active compounds was targeted...
Keywords: 201Tl(III)-complexation, Bleomycin, Biodistribution, SPECT, Fibrosarcoma
08/2006 | Radiochimica Acta, Oldenbourg WissenschaftsverlagBiological evaluation of 153Sm and 166Ho complexes with tetraazamacrocycles containing methylcarboxylate and/or methylphosphonate pendant arms
153Sm and 166Ho complexes with two series of tetraazamacrocyclic ligands containing methylcarboxylate and/or methylphosphonate pendant arms were synthesized and their charge, lipophilicity, protein binding and in vitro and in vivo behaviour evaluated...
Keywords: Radiolanthanides, Tetraazamacrocycles, Phosphonates, Carboxylates, Biodistribution
06/2007 | Radiochimica Acta, Oldenbourg WissenschaftsverlagRadiochemical and biological behaviour of 153Sm and 166Ho complexes anchored by a novel bis(methylphosphonate) tetraazamacrocycle
The novel bis(methylphosphonate) 2,2′-[4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl] diacetic acid, trans-H6DO2A2P, has been synthesized and characterized by multinuclear NMR spectroscopy (1H, 13C and 31P)...
Keywords: Radiolanthanides, Mixed-tetraazamacrocycles, Radiopharmaceuticals, Biodistribution
06/2007 | Radiochimica Acta, Oldenbourg WissenschaftsverlagDevelopment of [201Tl](III)-DTPA-human polyclonal antibody complex for inflammation detection
Thallium-201 (T1/2=3.04 d) in Tl+ form was converted to Tl3+ cation in presence of O3 in 6 M HCl controlled by RTLC/gel electrophoresis methods and used in the labeling of human polyclonal antibody (HIgG) after conjugation with freshly prepared cyclic DTPA-dianhydride...
Keywords: 201Tl(III)-complex, Biodistribution, Human polyclonal antibody, inflammation
11/2007 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag